Systemic treatments for metastatic cutaneous melanoma

A new Cochrane Review, published by Cochrane Skin, considers the effectiveness of treatments for systemic treatments for metastatic cutaneous melanoma. The review includes 122 randomized controlled trials involving 28,561 participants and considers interventions in five categories: conventional chemotherapy, biochemotherapy, immune checkpoint inhibitors, small molecule targeted drugs, and other agents. In comparison with chemotherapy, the evidence indicates that several treatments improve Progression Free Survival (PFS), and some improve overall survival. For more information, please see the full review available on the Cochrane Library.